Also known as:
Macrol (generic name: clarithromycin; brand names include: Maclar / Klaricid / Klacid / Clarimac /
Claribid) is used to treat many different types of bacterial infections affecting the skin and
respiratory system, including: Strep throat, Pneumonia, Sinusitis (inflamed sinuses), Tonsillitis
(inflamed tonsils), Acute middle ear infections, Acute flare-ups of chronic bronchitis.
It also is used to treat and prevent disseminated Mycobacterium avium complex (MAC) infection [a type
of lung infection that often affects people with human immunodeficiency virus (HIV)]. It is used in
combination with other medications to eliminate H. pylori, a bacteria that causes ulcers.
It also is used sometimes to treat other types of infections including Lyme disease (an infection that
may develop after a person is bitten by a tick), crypotosporidiosis (an infection that causes diarrhea),
cat scratch disease (an infection that may develop after a person is bitten or scratched by a cat),
Legionnaires' disease (a type of lung infection), and pertussis (whooping cough; a serious infection
that can cause severe coughing). It is also sometimes used to prevent heart infection in patients having
dental or other procedures.
This medication may be prescribed for other uses; ask your doctor or pharmacist for more
Macrol works by stopping the growth of or killing sensitive bacteria by interfering with their protein
The recommended daily dosage is 15 mg/kg/day divided every 12 hours for 10 days (up to the adult
dose). Refer to dosage regimens for mycobacterial infections in pediatric patients for additional dosage
For the treatment of disseminated infection due to Mycobacterium avium complex (MAC), Macrol Filmtab
and Macrol Granules are recommended as the primary agents. Macrol Filmtab and Macrol Granules should be
used in combination with other antimycobacterial drugs (e.g. ethambutol) that have shown in vitro
activity against MAC or clinical benefit in MAC treatment.
For treatment and prophylaxis of mycobacterial infections in adults, the recommended dose of Macrol is
500 mg every 12 hours.
For treatment and prophylaxis of mycobacterial infections in pediatric patients, the recommended dose
is 7.5 mg/kg every 12 hours up to 500 mg every 12 hours.
Macrol therapy should continue if clinical response is observed. Macrol can be discontinued when the
patient is considered at low risk of disseminated infection.
Overdose symptoms may include severe stomach pain, nausea, vomiting, or diarrhea.
Store at room temperature between 20 and 25 degrees C (68 and 77 degrees F) away from moisture and heat. Keep container tightly closed. Protect from light. Throw away any unused medicine after the expiration date. Keep out of the reach of children.